个人信息： 博士 讲师/硕士生导师

Email：6563@ldu.edu.cn

研究方向：1.食用菌重要农艺性状相关基因的挖掘和功能分析

                  2.食用菌的抗逆调控分子机制研究

                  3.食用菌在基质利用过程中纤维素酶合成调控的分子机制研究

个人简介：史灵燕，女，河北保定人。2020年9月至2025年6月就读于南京农业大学，获理学博士学位。2025年11月起就职于鲁东大学园艺学院，从事食用菌遗传育种相关研究。以第一/共同第一作者在Appl Environ Microbiol发表论文2篇，Top期刊Int J Biol Macromol发表论文1篇，Top期刊Communications Biology发表论文1篇，共参与发表学术论文8篇。

参与的项目：

国家自然科学基金：《转录因子Swi6调控灵芝三萜生物合成的分子机制研究》，编号：31972059，2020.01-2023.12

发表的论文列表：

[1] Shi L, Wang L, Liu R, Zhu J, Shi L, Ren A, Chen H, Zhao M. The GCN4-Swi6B module mediates low nitrogen-induced cell wall remodeling in Ganoderma lucidum. Appl Environ Microbiol. 2025 Apr 23;91(4):e0016425. (IF5:4.6)

[2] Shi L, Lian L, Wang L, Zhang S, Han Q, Shi L, Chen H, Zhao M. General control nonderepressible 4 activates the transcription of trehalose phosphorylase to improve trehalose production and abiotic stress tolerance in Ganoderma lucidum. Int J Biol Macromol. 2025 May 1;311(Pt 3):143840. (IF5:7.7)

[3] Lian L#, Shi LY#, Zhu J, Shi L, Ren A, You H, Liu R, Zhao M. GCN4 enhances the transcriptional regulation of areA by interacting with SKO1 to mediate nitrogen utilization in Ganoderma lucidum. Appl Environ Microbiol. 2022 Nov 22;88(22):e0132222. (IF5:4.6)

[4] Wang, L., Shi, L., Wang, H., Han, Q., Hu, Y., Zheng, Q., Dong, Z., Liu, R., Zhao, M., & Chen, H. GSK3 phosphorylates and activates trehalose-6-phosphate synthase to improve trehalose production and thermotolerance in Ganoderma lucidum. Communications Biology. 2025;8(1):1762.（IF5:5.6）

[5] Lian LD, Shi LY, Zhu J, Liu R, Shi L, Ren A, Yu HS, Zhao MW. GlSwi6 positively regulates cellulase and Xylanase activities through intracellular Ca²⁺ signaling in Ganoderma lucidum. J Fungi (Basel). 2022 Feb 14;8(2):187. (IF5:4.5)

[6] Wang L, Shi LY, Zhang S, Ma, J., Zhang, C., Chen, H., & Zhao, M. The APSES transcription factor Swi6B upregulates CATALASE 1 transcription to enhance oxidative stress tolerance of Ganoderma lucidum[J]. Appl Environ Microbiol, 2025a, 91(7):e0067925. （IF5:4.9）

[7] Han X, Wang Z, Shi LY, Zhu J, Shi L, Ren A, Zhao M. Phospholipase D and phosphatidic acid mediate regulation in the biosynthesis of spermidine and ganoderic acids by activating GlMyb in Ganoderma lucidum under heat stress. Environ Microbiol. 2022 Nov;24(11):5345-5361. (IF5:5.2)

[8] Han X, Wang Z, Shi LY, Wei ZY, Shi L, Zhao M. Spermidine enhances the heat tolerance of Ganoderma lucidum by promoting mitochondrial respiration driven by fatty acid β-oxidation. Appl Environ Microbiol. 2025 Feb 19;91(2):e0097924. (IF5:4.6)